Mosaicing of Dynamic Mesentery Video with Gradient Blending

In the aspect of medical imaging, it is crucial to obtain certain structures or even cellular features in microscopic resolution. Unfortunately, the field of view is inherently limited by the capability of capturing instruments. Thus, mosacing of such microstructure is of utmost importance in order to restore original visual information for establishing broad structure morphology. Large panoramic images with microscopic resolution can be rewarding and practical for conducting comprehensive observation and exploration of the object of interest and surrounding biological structure. But mosaicing can be challenging if there are deformable, motion-blurred, textureless, feature-poor frames in the sequence. Feature-based methods perform poorly in such cases for the lack of distinctive keypoints. Standard single block correlation matching strategies might not provide robust registration due to deformable content. In addition, the panorama suffers if there is motion blur present in a sequence. To handle these challenges, we propose a novel algorithm, Deformable Normalized Cross Correlation (DNCC) image matching with RANSAC to establish robust registration. Besides, to produce seamless panorama from motion-blurred frames we present Edge blending method based on image gradient information. The DNCC algorithm is applied on Frog Mesentery sequence. Our result is compared with PSS ~\cite{bay2006surf, matlab} method to establish the efficiency and robustness of the proposed DNCC method.