Association between Dynamic Functional Connectivity and Intelligence

Several studies have explored the relationship between intelligence and neuroimaging features. However, little is known about whether the temporal variations of functional connectivity of the brain regions at rest are relevant to the differences in intelligence. In this study, we have used the fMRI data and intelligence scores of 50 healthy adult subjects from the Human Connectome Project (HCP) database. We have investigated the correlation between individual intelligence scores and the total power of the high frequency components of the Fast Fourier transform (FFT) of the dynamic functional connectivity time series of the brain regions. We have found temporal variations of specific functional connections highly correlated with the individual intelligence scores. In other words, functional connections of individuals with high levels of the intelligence have smoother temporal variation or higher temporal stability than those of the individuals with low intelligence levels.