Gadolinium-Free Crohn'S Disease Assessment From Magnetic Resonance Enterography Data

Magnetic resonance enterography (MRE) based indices are widely used to assess the severity of Crohn’s disease (CD) in patients. The manual calculation of these indices by radiologists is both time consuming and subject to bias. Specifically, terminal-ileum (TI) wall-thickening is challenging to estimate, especially from gadolinium-free T2-weighted MRI data. We present a system to segment the TI and classify wall-thickening automatically from T2-weighted MRE data. We evaluated our segmentation model on 180 T2-weighted MRE scans and reached a dice score of 0.635. We tested the capacity of our system to distinguish between patients with and without high wall thickness (>8mm vs.